Celexa

Jul 20, 2022

Generic name:  citalopram  [ si-TAL-o-pram ]
Drug class:  Selective serotonin reuptake inhibitors

What is Celexa?

Celexa is an antidepressant belonging to a group of drugs called  selective serotonin reuptake inhibitors  (SSRIs).

Celexa is a prescription medicine used to treat  depression .

Celexa is also used to treat  major depressive disorder (MDD) .

Warnings

Celexa can cause a serious heart problem. Call your doctor right away if you have chest pain, fast or pounding heartbeats, shortness of breath, and sudden  dizziness .

You should not use Celexa if you also take pimozide, as the combination can cause problems with your heart rhythm.

Do not use Celexa if you have used a MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine) or have received a methylene blue injection. A fatal reaction may occur.

People with depression or mental illness may have thoughts about suicide. Some young people may have increased suicidal thoughts when first starting a medicine to treat depression. Tell your doctor right away if you have any sudden changes in mood or behavior, or thoughts about suicide.

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Do not stop using Celexa without first asking your doctor.

Before taking this medicine

You should not use Celexa if you are allergic to citalopram or escitalopram (Lexapro), or if you also take  pimozide .

Do not use Celexa within 2 weeks before or after using an  MAO inhibitor  in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include  isocarboxazid ,  linezolid ,  methylene blue  injection,  phenelzine , and  tranylcypromine .

To make sure Celexa is safe for you, tell your doctor if you have ever had:

  • heart problems;
  • long QT syndrome  (in you or a family member);
  • high blood pressure ;
  • a stroke;
  • bleeding problems;
  • sexual problems;
  • liver or kidney disease;
  • narrow-angle  glaucoma ;
  • seizures  or  epilepsy ;
  • bipolar disorder  (manic depression); or
  • an electrolyte imbalance (such as low levels of potassium, magnesium, or sodium in your blood).

Tell your doctor if you also use stimulant medicine, opioid medicine,  herbal products , or medicine for depression, mental illness,  Parkinson’s disease ,  migraine  headaches, serious infections, or prevention of  nausea and vomiting . An interaction with citalopram could cause a serious condition called  serotonin syndrome .

People with depression or mental illness may have thoughts about suicide. Some young people may have increased suicidal thoughts when first starting a medicine to treat depression. Stay alert to changes in your mood or symptoms. Your family or caregivers should also watch for sudden changes in your behavior.

Taking Celexa during pregnancy could harm the baby, but stopping the medicine may not be safe for you. Do not start or stop Celexa without asking your doctor.

You should not breastfeed while taking Celexa.

How should I take Celexa?

Take Celexa exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.

Your symptoms may not improve for up to 4 weeks.

Tell your doctor if you have any changes in sexual function, such as loss of interest in sex, trouble having an orgasm, or (in men) problems with erections or ejaculation. Some sexual problems can be treated.

If you stop using Celexa suddenly, you may have unpleasant symptoms (such as  agitation , confusion, tingling or electric shock feelings). Ask your doctor before stopping the medicine.

Store Celexa t room temperature away from moisture and heat.

Dosing information

Usual Adult Dose of Celexa for Depression:

Initial dose: 20 mg orally once a day
Maintenance dose: 20 to 40 mg orally once a day
Maximum dose: 40 mg orally per day

Comments:
-The initial dose may be increased if necessary to 40 mg once a day after at least 1 week of therapy.
-Doses of 60 mg/day did not demonstrate an advantage in efficacy over 40 mg/day doses.
-Acute episodes of depression may require several months or more of sustained pharmacologic therapy

Use: Treatment of depression

Usual Geriatric Dose of Celexa for Depression:

Over 60 years of age:
Recommended dose: 20 mg orally once a day

Comments:
-Doses of 60 mg/day did not demonstrate an advantage in efficacy over 40 mg/day doses.
-Acute episodes of depression may require several months or more of sustained pharmacologic therapy.

Use: Treatment of depression

Detailed Celexa dosage information

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Celexa?

Ask your doctor before taking a nonsteroidal anti-inflammatory drug (NSAID) such as  aspirin ,  ibuprofen ,  naproxen ,  Advil ,  Aleve ,  Motrin , and others. Using an NSAID with Celexa may cause you to bruise or bleed easily.

Avoid drinking alcohol.

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

Celexa side effects

Get emergency medical help if you have signs of an allergic reaction to Celexa:  hives , rash, blisters; fever, joint pain; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your doctor right away if you have new or sudden changes in mood or behavior, including new or worse depression or  anxiety ,  panic attacks , trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, more active or talkative, or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;
  • blurred vision,  eye pain  or redness, seeing halos around lights;
  • fast or pounding heartbeats, pain or fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out);
  • a seizure;
  • manic episodes – racing thoughts, increased energy, decreased need for sleep, risk-taking behavior, being agitated or talkative;
  • severe nervous system reaction – very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors; or
  • low blood sodium –  headache , confusion, problems with thinking or memory, weakness, feeling unsteady.

Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering,  fast heart rate , muscle stiffness, twitching, loss of coordination,  nausea ,  vomiting , or  diarrhea .

Common Celexa side effects may include:

  • sexual problems;
  • dizziness, drowsiness;
  • dry mouth, thirst, increased sweating or urination;
  • loss of appetite, nausea, diarrhea,  constipation ;
  • feeling anxious, agitated, or shaky;
  • feeling weak or tired;
  • sleep problems ( insomnia );
  • yawning;
  • increased muscle movement;
  • nosebleeds ,  heavy menstrual bleeding ; or
  • cold symptoms  such as stuffy nose, sneezing,  sore throat .

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Celexa side effects  (more detail)

What other drugs will affect Celexa?

Celexa can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections,  asthma , heart problems, high blood pressure, depression, mental illness, cancer,  malaria , or  HIV .

Tell your doctor about all your current medicines. Many other drugs can interact with citalopram, especially:

  • cimetidine ;
  • a blood thinner ( warfarin ,  Coumadin ,  Jantoven );
  • a diuretic or “water pill”;
  • lithium ;
  • St. John’s wort ;
  • tramadol ; or
  • tryptophan  (sometimes called L-tryptophan).

This list is not complete and many other drugs may interact with citalopram. This includes prescription and over-the-counter medicines,  vitamins , and  herbal products . Not all possible drug interactions are listed here.

source :: https://www.drugs.com/celexa.html