Generic name: clobetasol topical [ kloe-BAY-ta-sol ]
Brand names: Clobex, Clodan, Impoyz, Olux, Olux-E, … show all 17 brands
Drug class: Topical steroids
What is clobetasol topical?
Clobetasol is a highly potent corticosteroid that helps reduce inflammation in the body.
Clobetasol topical (for the skin) is used to treat inflammation and itching caused by plaque psoriasis and skin conditions that respond to corticosteroid medication.
It is available in a cream, gel, ointment, lotion, solution, foam or spray.
Do not use clobetasol topical to treat acne, rosacea, or a rash around the mouth.
Use care when putting on a large part of the skin or where there are open wounds. Talk with the doctor.
Clobetasol may cause harm if swallowed. If swallowed, call a doctor or poison control center right away.
This drug may raise the chance of cataracts or glaucoma. Talk with your doctor.
It may affect growth in children and teens in some cases. They may need regular growth checks.
If you are breast-feeding, do not apply clobetasol cream, gel, ointment, lotion, solution, foam or spray to the nipple or the area around it.
Before taking this medicine
You should not use clobetasol topical if you are allergic to it.
To make sure this drug is safe for you, tell your doctor if you have ever had:
- any type of skin infection ;
- a skin reaction to any steroid medicine;
- liver disease ; or
- an adrenal gland disorder.
Steroid medicines can increase the glucose (sugar) levels in your blood or urine. Tell your doctor if you have diabetes.
It is not known whether clobetasol topical will harm an unborn baby. Tell your doctor if you are pregnant.
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. If you apply this drug to your chest, avoid areas that may come into contact with the baby’s mouth.
Clobetasol is not approved for use by anyone younger than 12 years old. Some brands or forms of this medicine are for use only in adults 18 and over.
Children can absorb larger amounts of this medicine through the skin and may be more likely to have side effects.
How should I use clobetasol?
Use this drug exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.
Do not take by mouth. Topical medicine is for use only on the skin. Rinse with water if this medicine gets in your eyes or mouth.
Do not use clobetasol on broken or infected skin. Also avoid using this medicine in open wounds.
Wash your hands before and after using this drug, unless you are using the medicine to treat the skin on your hands.
Apply a thin layer of medicine to the affected skin and rub it in gently. Do not apply this medicine over a large area of skin unless your doctor has told you to.
Do not cover the treated skin area with a bandage or other covering unless your doctor tells you to. Covering treated areas can increase the amount of medicine absorbed through your skin and may cause harmful effects.
If you are treating the diaper area, do not use plastic pants or tight-fitting diapers.
This medicine is for short-term use only (2 weeks, or up to 4 weeks for scalp psoriasis ). Follow your doctor’s dosing instructions very carefully.
If you use clobetasol to treat plaque psoriasis, you should stop using the medicine once your skin symptoms are controlled.
Call your doctor if your symptoms do not improve, or if they get worse.
You should not stop using this drug suddenly. Follow your doctor’s instructions about tapering your dose.
Store at room temperature away from moisture and heat. Keep from freezing.
Clobetasol foam is flammable. Do not use near high heat or open flame. Do not smoke until the foam has completely dried on your skin.
Detailed Clobetasol topical dosage information
What happens if I miss a dose?
Apply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.
High doses or long-term use of clobetasol can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence , or loss of interest in sex.
What should I avoid while using clobetasol?
Avoid applying clobetasol topical to your face, underarms, or groin area.
Do not use this medicine to treat any condition that has not been checked by your doctor.
Avoid using other topical steroid medications on the areas you treat with clobetasol unless your doctor tells you to.
Clobetasol side effects
Get emergency medical help if you have signs of an allergic reaction to clobetasol: hives ; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- worsening of your skin condition;
- redness, warmth, swelling, oozing, or severe irritation of any treated skin;
- blurred vision, tunnel vision, eye pain , or seeing halos around lights;
- high blood sugar – increased thirst, increased urination, dry mouth, fruity breath odor; or
- possible signs of absorbing this medicine through your skin – weight gain in your face and shoulders, slow wound healing, skin discoloration, thinning skin, increased body hair, tiredness, mood changes, menstrual changes, sexual changes.
Common side effects may include:
- burning, itching, swelling, or irritation of treated skin;
- dry or cracking skin;
- redness or crusting around your hair follicles;
- spider veins;
- stretch marks, thinning skin;
- rash or hives;
- acne; or
- temporary hair loss .
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Clobetasol topical side effects (more detail)
What other drugs will affect clobetasol?
Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins , and herbal products .