Dutasteride 

Jul 21, 2022

Generic name: dutasteride [ doo-TAS-ter-ide ]
Brand name: Avodart
Dosage form: oral capsule (0.5 mg)
Drug class:  5-alpha-reductase inhibitors

What is dutasteride?

Dutasteride is used to treat  benign prostatic hyperplasia  (BPH) in men with an  enlarged prostate . Dutasteride helps improve urinary flow and may also reduce your need for prostate surgery later on.

dutasteride is for use in men only.

Dutasteride may also be used for purposes not listed in this medication guide.

Warnings

Dutasteride should never be taken by a woman or a child.

Dutasteride can cause birth defects if a woman is exposed to it during pregnancy. Dutasteride capsules should not be handled by a woman who is pregnant or may become pregnant.

Before taking this medicine

You should not use dutasteride if you are allergic to dutasteride or  finasteride .

Dutasteride should never be taken by a woman or a child. Dutasteride can be absorbed through the skin, and women or children should not be permitted to handle dutasteride capsules.

Tell your doctor if you have ever had:

  • liver disease .

Using dutasteride may increase your risk of developing  prostate cancer . Your doctor will test your prostate specific antigen (PSA) to check for cancer while you are using this medicine.

Dutasteride is not for use by women, and this medicine can cause birth defects if a woman is exposed to it during pregnancy. Dutasteride capsules should not be handled by a woman who is pregnant or who may become pregnant.

If a woman accidentally comes into contact with this medication from a leaking capsule, wash the area with soap and water right away.

How should I take dutasteride?

Your doctor will perform tests to make sure you do not have other conditions that would prevent you from safely using dutasteride.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Take the medicine at the same time each day, with or without food.

Swallow the capsule whole and do not crush, chew, break, or open it.

It may take up to 6 months or longer before you receive the full benefit of taking dutasteride. Your doctor will determine how long to treat you with this medicine. Keep using the medication as directed.

You will need frequent medical tests.

Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking dutasteride?

Do not donate blood while taking dutasteride and for at least 6 months after your treatment ends. Dutasteride can be carried in the blood and could cause birth defects if a pregnant women receives a transfusion with blood that contains dutasteride.

Dutasteride side effects

Get emergency medical help if you have signs of an allergic reaction ( hives , difficult breathing, swelling in your face or throat) or a severe skin reaction (fever,  sore throat , burning eyes, skin pain, red or purple  skin rash  with blistering and peeling).

Common side effects of dutasteride may include:

  • decreased libido (sex drive);
  • decreased amount of semen released during sex;
  • impotence  (trouble getting or keeping an erection); or
  • breast tenderness or enlargement.

The sexual side effects of dutasteride may continue after you stop taking dutasteride. Talk to your doctor if you have concerns about these side effects.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Dutasteride side effects  (more detail)

Dutasteride dosing information

Usual Adult Dose for Benign Prostatic Hyperplasia:

0.5 mg orally once a day

Use: Treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate to reduce the risk of acute  urinary retention  (AUR) and BPH-related surgery.

Detailed Dutasteride dosage information

What other drugs will affect dutasteride?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Other drugs may affect dutasteride, including prescription and over-the-counter medicines,  vitamins , and  herbal products . Tell your doctor about all your current medicines and any medicine you start or stop using.

source :: https://www.drugs.com/mtm/dutasteride.html