Injectafer

Jul 26, 2022

Generic name:  ferric carboxymaltose  [ FER-ik-kar-BOX-ee-MAWL-tose ]
Drug class:  Iron products

What is Injectafer?

Injectafer is an injectable iron replacement product. You normally get iron from the foods you eat. Iron helps your body produce red blood cells that carry oxygen through your blood to tissues and organs.

Injectafer is used in adults to treat  iron deficiency anemia (IDA)  (a lack of red blood cells caused by having too little iron in the body).

Injectafer is given to adults with IDA and  chronic kidney disease  (not on dialysis), or to adults with IDA when iron taken by mouth is not effective.

Injectafer is usually given after oral (taken by mouth) iron replacement medicines have been tried without success.

Warnings

You should not use Injectafer if you have iron overload disorder, or anemia that is not caused by iron deficiency.

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or  allergies .

Before taking this medicine

You should not use Injectafer if you are allergic to ferric carboxymaltose.

To make sure Injectafer is safe for you, tell your doctor if you have ever had:

  • high blood pressure ; or
  • an allergic reaction to iron injected into a vein.

Tell your doctor if you are pregnant or plan to become pregnant. It is not known if ferric carboxymaltose will harm an unborn baby, but this medicine may cause severe reactions in the mother that could affect the baby’s heartbeat.

Having iron deficiency anemia during pregnancy may increase the risk of premature birth or low birth weight. The benefit of treating this condition with Injectafer may outweigh any risks to the baby.

If you are breastfeeding, tell your doctor if you notice  diarrhea  or  constipation  in the nursing baby.

How is Injectafer given?

Injectafer is injected into a vein by a healthcare provider.

Tell your medical caregivers if you feel any burning or pain when Injectafer is injected.

You will be watched for at least 30 minutes to make sure you do not have an allergic reaction.

This medicine is usually given in 2 doses, 7 days apart.

You may need frequent medical tests, even if you have no symptoms.

Dosing information

Usual Adult Dose for Iron Deficiency Anemia:

Patients weighing 50 kg or more: Two doses of 750 mg via slow IV push or infusion separated by at least 7 days
Patients weighing less than 50 kg: Two doses of 15 mg/kg via slow IV push or infusion separated by at least 7 days
Maximum dose: Total cumulative dose should not exceed 1500 mg of iron per course

Comments:
-The dosage is expressed in mg of elemental iron.
-Treatment may be repeated if iron deficiency anemia recurs

Use: Treatment of iron deficiency anemia in adults with an intolerance or unsatisfactory response to oral iron and in adults with non-dialysis dependent chronic kidney disease

Detailed Injectafer dosage information

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your Injectafer injection.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include pain, cough, wheezing, shortness of breath,  coughing up blood ,  weight loss , or slowed growth in a child.

What should I avoid after receiving Injectafer?

Do not take iron supplements or a vitamin/mineral supplement that your doctor has not prescribed or recommended.

Injectafer side effects

Get emergency medical help if you have signs of an allergic reaction to Injectafer:  hives ; feeling like you might pass out; wheezing, difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • increased blood pressure –  dizziness ,  nausea , sudden warmth or redness in your face, severe  headache , pounding in your neck or ears;
  • low levels of phosphorus in your blood – confusion, bone pain, muscle weakness; or
  • high levels of iron stored in your body – feeling weak or tired, joint pain, finger pain, stomach pain, weight loss, irregular heartbeats, fluttering in your chest.

Common Injectafer side effects may include:

  • nausea;
  • dizziness;
  • high blood pressure;
  • flushing (warmth, redness, or tingly feeling); or
  • low phosphorus levels.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Injectafer side effects  (more detail)

What other drugs will affect Injectafer?

Other drugs may interact with ferric carboxymaltose, including prescription and over-the-counter medicines,  vitamins , and  herbal products . Tell your doctor about all other medicines you use.

source :: https://www.drugs.com/injectafer.html